Santo Domingo to Samana bus
The bus from Santo Domingo to Samana takes 2 h 30 min and has 3 daily departures. Bookable on Guagualine soon.
Last verified: 2026-07-20 · Caribe Tours
Initial research data. We confirm by phone with the operator before every sale.
Santo Domingo → Samana bus schedule
| Departure | Operator | Terminal |
|---|---|---|
| 07:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 11:00 | Caribe Tours | Caribe Tours Terminal Santo Domingo |
| 15:00 48 h cutoff | Caribe Tours | Caribe Tours Terminal Santo Domingo |
Roughly every 4 hours. Confirm by phone.
The last departure of the day is never sold with a Guagualine booking: if your bus fails there must always be a later departure as plan B.
Local schedules and prices are indicative and can change without notice from the operator. We verify them before confirming every booking.
Coming soon on this route
We are closing agreements with operators on this route. Send us your trip on WhatsApp and we will let you know as soon as sales open.
The Guagualine guarantee
If your departure is cancelled or the operator does not honor your seat, we rebook you on the next departure, upgrade you to a better transfer or refund 100% of what you paid. Your choice.
The guarantee covers the amount paid to Guagualine. The transport contract is between the passenger and the operator named on the voucher.
Terminals on this route
Caribe Tours Terminal Santo Domingo
Av. 27 de Febrero esq. Leopoldo Navarro, Santo Domingo
What to know before you board
The biggest network, and the busiest
Caribe Tours covers nearly the whole country, so its morning departures sell out first. Mid afternoon runs usually have more space.
Checked luggage gets a tag
You receive a numbered stub for your suitcase. Keep it: without it they may not release your luggage on arrival.
Fares revised in May 2026
Prices went up in May 2026 on several routes. Any fare you see on older blogs is out of date.
Wifi and a movie on board
Long distance coaches usually have patchy wifi and a movie playing loud. Bring headphones.
Timetables change without notice
Dominican operators adjust departures for season, roadworks or demand, and they almost never publish it. That is why we verify by phone before confirming each request and show the last check date on this page.
We never sell the last departure of the day
If your bus fails there has to be a later one to rebook you on. That is the rule that lets us offer a real guarantee.